The STI Clinic News > Immunity Drop During Ovulation Makes Women Susceptible to STIs
# Friday, January 6, 2012
Posted: Friday, January 6, 2012 | Categories: Women's Sexual Health

If there wasn’t already enough reason to practice safe sex consistently, we have recently been reminded that there is a natural weakness in female immunity as ovulation occurs, more than at any other time throughout the menstrual cycle. This is thought to occur in order to allow sperm to survive a potential immune response once inside the body of the female and go on to fertilise an egg. According to a recent study, this has the potential to make women more susceptible to a sexually transmitted infection while ovulating.

A study was carried out at the Laboratorio de Inmunobiologia Moleculare at the hospital Gregario Maranon and Complutense University, Madrid, and the team used mice for the purposes of the study. They found that estradiol, a sex hormone, which is mostly made in the ovaries and the placenta (in pregnancy) decreased the immune response in female mice leaving them more exposed to potential infections including yeast infections and sexually transmitted bacteria and viruses.

Since the mice were only tested using candida albicans (the cause of yeast infection), this is not enough proof to suggest that women would be more susceptible to all sexually transmitted infections during ovulation and so further investigations will be carried out in this area although the scientists behind the study are confident that their finding will translate to other infections.


How Our Service Works

  • Order your
    STI test online
  • Discreet package
    arrives next day
  • Provide a sample and post in pre-paid envelope
  • Access results online
How it works - order a test, provide sample and get results online


UK +44 (0)20 7125 0367



2 Wingate Business Exchange, 64-66 Wingate Square
London SW4 0AF

Registered Address

7 Tufton Street
London SW1P 3QB

The STI Clinic is owned and operated by Online Medical Services Limited. Any medical service required is contracted to be provided by Online Clinic (UK) Limited, which is licensed by the Care Quality Commission. Testing is undertaken at The Doctors Laboratory, which is registered with Clinical Pathology Accreditation.

  • The Doctors Laboratory
  • Clinical Pathology Accreditation logoClinical Pathology Accreditation no. 1954
  • Information Commissioner's OfficeData Protection Act registered
    ICO registration no. Z2782183
Visa and Visa Debit accepted Master accepted American Express accepted