The STI Clinic News > Mycoplasma Genitalium
# Thursday, 12 June 2014
Posted: Thursday, 12 June 2014 | Categories: Mycoplasma Genitalium

One of the questions we get asked quite frequently is whether or not Mycoplasma Genitalium should be treated. The reason we get asked this question is that a number of people have been told by NHS staff that they do not test for this infection as it is very common and does not cause any problems if left untreated. This advice really flies in the face of most of the scientific evidence that we have to hand.

It is certainly true that many women who test positive for Mycoplasma Genitalium do not have any outward symptoms but there is an association between Mycoplasma Genitalium and tubal factor infertility. Many women do of course have outward symptoms and are not offered the right treatment as Mycoplasma has not been detected by the NHS so the patient is given a course of treatment that we know through clinical experience and controlled studies to be not the optimum choice.

The vast majority of men who test positive for Mycoplasma Genitalium do have symptoms and are normally diagnosed with NSU by the NHS. Again, this can lead to the prescription of a sub-optimal course of treatment.

Our recommendation is that the front line treatment for Mycoplasma Genitalium should be a 5 day course of Azithromycin, with 500 mg on day one and the four subsequent doses of 250 mg. This produces the highest cure rate of all the non-quinolone medications. If this treatment fails (and we have not had one single case where it has failed) then we would recommend a course of Moxifloxacin.

You can read more about Mycoplasma Genitalium here.

# Friday, 09 March 2012
Posted: Friday, 09 March 2012 | Categories: Mycoplasma Genitalium

Recent research has found that the bacterial infection, Mycoplasma genitalium, an infection which can be transmitted sexually, increased the risk of African women becoming infected with HIV.

The Mycoplasma Genitalium bacterium was only discovered in 1980 and research into this relatively new infection is on-going. Previous data from a bigger study of HIV in women from Zimbabwe and Uganda was used in order to assess the effects of M. genitalium on the risk of contracting HIV. At the study’s outset, the women were all HIV free. It was discovered that 190 women from the study group had become infected with HIV after follow-up meetings. These women and the women who were not infected were tested for the bacterial infection M. genitalium and it was found that the infection was present in 15% of the women who went on to develop HIV as opposed to 6.5% among the women who did not go on to contract HIV.

The presence of other STIs, and especially infections such as herpes simplex II, also increased the risk of contracting HIV. M. genitalium was however more commonly detected in this particular study than other STIs such as chlamydia and gonorrhoea.

Much research is being carried out in the area of M. genitalium as there is still little known about this infection. The NHS does not test for it in their GUM clinics at the current time. A short course of antibiotics can eliminate the infection. We always advise patients who are having symptoms to have a full screen but maybe getting tested for Mycoplasma Genitalium as part of a routine STI check-up should be the norm as its prevalence increases.

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