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    <title>The STI Clinic - Herpes</title>
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    <copyright>The STI Clinic</copyright>
    <lastBuildDate>Fri, 03 May 2013 18:43:03 GMT</lastBuildDate>
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      <dc:creator>Robert Mackay</dc:creator>
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      <title>Could Herpes Virus Impair Memory?</title>
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      <link>http://www.thesticlinic.com/news/2013/05/03/CouldHerpesVirusImpairMemory.aspx</link>
      <pubDate>Fri, 03 May 2013 18:43:03 GMT</pubDate>
      <description>&lt;p class=MsoNormal style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" align=justify&gt;
&lt;font color=#000000&gt;Some viruses, such as the herpes varicella-zoster virus, never
leave the infected persons body. Instead, they remain dormant in the central nervous
system and flare up occasionally. Yet, the long-term consequences of having certain
viruses remain relatively unexplored. However, one study that has come to our attention
recently has tried to do this. Here we consider the findings of a study that sought
to see whether a cumulative presence of infections would have an impact on cognitive
functioning.&lt;/font&gt;
&lt;/p&gt;
&lt;p class=MsoNormal style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" align=justify&gt;&lt;?xml:namespace prefix = "o" /&gt;
&lt;o:p&gt;
&lt;font color=#000000&gt;&amp;nbsp;&lt;/font&gt;
&lt;/o:p&gt;
&lt;/p&gt;
&lt;p class=MsoNormal style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" align=justify&gt;
&lt;font color=#000000&gt;The study, which was published in &lt;i style="mso-bidi-font-style: normal"&gt;Neurology&lt;/i&gt; included
a total of 1625 participants. At the start of the study, the participants were 69
years old on average. The studies lasted eight years, and during this time the researchers
performed a range of tests and assessments. They analysed blood samples for herpes
simplex 1 and 2 and cytomegalovirus. In addition to that, they &lt;a href="http://www.empowher.com/sexual-well-being/content/new-study-suggests-herpes-virus-affects-memory-older-adults" target=_New&gt;screened
all the participants for Chlamydia pneumoniae and helicobacter pylori&lt;/a&gt;. Lastly,
they performed annual tests to assess changes in cognitive abilities such as memory.
The key findings indicated that a high level of infection was related to an increased
risk of memory deficiencies. This association remained even after mental sharpness,
education, smoking, heart disease and diabetes were taken into account. However, the
researchers were keen to stress that their study reflected an association and not
causation. As such, they recommended that further studies be carried out within this
field.&lt;/font&gt;
&lt;/p&gt;
&lt;p class=MsoNormal style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" align=justify&gt;
&lt;o:p&gt;
&lt;font color=#000000&gt;&amp;nbsp;&lt;/font&gt;
&lt;/o:p&gt;
&lt;/p&gt;
&lt;p class=MsoNormal style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" align=justify&gt;
&lt;font color=#000000&gt;Although it looks like an acceptable study on the face of it,
we cannot help but feel a bit sceptical about it. One of the reasons for that is that
many aspects relating to the rationale were not sufficiently clarified in the publication.
In particular, it was not mentioned how long the individuals had had each virus before
the researchers detected an increased risk for poorer memory. As such, there was no
baseline to compare the findings to. Similarly, we cannot help but feel that a case-control
study that sought to give participants a battery of rigorous and reliable cognitive
tests would have been more suitable for the type of research that was being carried
out. That’s not to say that the current study lacked qualities worth replicating.
The sample and the adjustment for confounding variables as well as the long follow
up period are commendable. Therefore, it is our hope that further studies aiming to
confirm and extend on these findings will be undertaken.&lt;/font&gt;
&lt;/p&gt;
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      <comments>http://www.thesticlinic.com/news/CommentView,guid,0aefb9a9-c75f-44a4-9654-bca4d492eda6.aspx</comments>
      <category>Herpes</category>
    </item>
    <item>
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      <dc:creator>Robert Mackay</dc:creator>
      <wfw:comment>http://www.thesticlinic.com/news/CommentView,guid,c373f51a-a630-4881-a909-c61801b9f45a.aspx</wfw:comment>
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        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal">
          <font color="#000000">It is rare for most people to think about infants when it comes
to sexually transmitted infections. Yet reports concerning HIV and herpes in infants
have been cropping up rather regularly in the media lately.</font>
        </p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal">
          <font color="#000000">
          </font> 
</p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">It was recently reported that two infants in New York City were
infected with herpes as a result of being circumcised in a rather controversial way.
Specifically, in the procedure called metzitzah b'peh, the practitioner was required
to orally suck the baby’s penis in order to cleanse the wound. Although this is in
stark contrast to the way prevailing circumcision procedures are carried out (where
sterile tools are used to clean the wound), there is still a minority of families
that prefer this practice.</font>
        </p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">
          </font> 
</p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">When an infant is infected with a virus, the effects of it are
different from what they would be for an adult, as an infant does not have a fully
developed immune system. According to the Centre for Disease Control and Prevention,
there have been past cases where infants’ herpes infection has led to brain damage
and even death. In milder effects, the infants have had a fever (which is not unusual
in adults). Given this, it is not surprising that the health department has informed
medical staff to be vigilant to cases of male infant sepsis and to ask whether this
could be due to circumcision. In addition to that, regulations have been passed that
require that parents of a child sign a consent form that allows the oral sucking to
occur during the procedure.</font>
        </p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">
          </font> 
</p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">Although the two infants that were infected have survived, it
is not clear whether there will be any long-term effects to their health. In general,
the prognosis of <a href="http://emedicine.medscape.com/article/964866-overview" target="_New">neonatal
herpes infection</a> is unclear as contracting this illness is rather unusual and
the known cases have not reached adulthood yet. As such, it also raises questions
of how to treat these cases.</font>
        </p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
 
</p>
        <p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class="MsoNormal" align="justify">
          <font color="#000000">Naturally these cases should not be taken lightly. However,
it is also important to remember that parents should be allowed the choice of how
to circumcise their children. Perhaps, rather than having parents sign consent for
the procedure, it would be more prudent to ensure that the practitioners carrying
out the procedure are not posing a risk to the child.</font>
        </p>
        <img width="0" height="0" src="http://www.thesticlinic.com/news/aggbug.ashx?id=c373f51a-a630-4881-a909-c61801b9f45a" />
      </body>
      <title>Neonate Herpes Infection During Orthodox Circumcision</title>
      <guid isPermaLink="false">http://www.thesticlinic.com/news/PermaLink,guid,c373f51a-a630-4881-a909-c61801b9f45a.aspx</guid>
      <link>http://www.thesticlinic.com/news/2013/04/15/NeonateHerpesInfectionDuringOrthodoxCircumcision.aspx</link>
      <pubDate>Mon, 15 Apr 2013 09:46:44 GMT</pubDate>
      <description>&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal&gt;
&lt;font color=#000000&gt;It is rare for most people to think about infants when it comes
to sexually transmitted infections. Yet reports concerning HIV and herpes in infants
have been cropping up rather regularly in the media lately.&lt;/font&gt;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal&gt;
&lt;font color=#000000&gt;&lt;/font&gt;&amp;nbsp;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;It was recently reported that two infants in New York City were
infected with herpes as a result of being circumcised in a rather controversial way.
Specifically, in the procedure called metzitzah b'peh, the practitioner was required
to orally suck the baby’s penis in order to cleanse the wound. Although this is in
stark contrast to the way prevailing circumcision procedures are carried out (where
sterile tools are used to clean the wound), there is still a minority of families
that prefer this practice.&lt;/font&gt;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;&lt;/font&gt;&amp;nbsp;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;When an infant is infected with a virus, the effects of it are
different from what they would be for an adult, as an infant does not have a fully
developed immune system. According to the Centre for Disease Control and Prevention,
there have been past cases where infants’ herpes infection has led to brain damage
and even death. In milder effects, the infants have had a fever (which is not unusual
in adults). Given this, it is not surprising that the health department has informed
medical staff to be vigilant to cases of male infant sepsis and to ask whether this
could be due to circumcision. In addition to that, regulations have been passed that
require that parents of a child sign a consent form that allows the oral sucking to
occur during the procedure.&lt;/font&gt;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;&lt;/font&gt;&amp;nbsp;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;Although the two infants that were infected have survived, it
is not clear whether there will be any long-term effects to their health. In general,
the prognosis of &lt;a href="http://emedicine.medscape.com/article/964866-overview" target=_New&gt;neonatal
herpes infection&lt;/a&gt; is unclear as contracting this illness is rather unusual and
the known cases have not reached adulthood yet. As such, it also raises questions
of how to treat these cases.&lt;/font&gt;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&amp;nbsp;
&lt;/p&gt;
&lt;p style="TEXT-ALIGN: justify; MARGIN: 0cm 0cm 0pt" class=MsoNormal align=justify&gt;
&lt;font color=#000000&gt;Naturally these cases should not be taken lightly. However, it
is also important to remember that parents should be allowed the choice of how to
circumcise their children. Perhaps, rather than having parents sign consent for the
procedure, it would be more prudent to ensure that the practitioners carrying out
the procedure are not posing a risk to the child.&lt;/font&gt;
&lt;/p&gt;
&lt;img width="0" height="0" src="http://www.thesticlinic.com/news/aggbug.ashx?id=c373f51a-a630-4881-a909-c61801b9f45a" /&gt;</description>
      <comments>http://www.thesticlinic.com/news/CommentView,guid,c373f51a-a630-4881-a909-c61801b9f45a.aspx</comments>
      <category>Herpes</category>
    </item>
    <item>
      <trackback:ping>http://www.thesticlinic.com/news/Trackback.aspx?guid=79102573-35cd-40b2-9bc9-608fd7b5eb43</trackback:ping>
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      <dc:creator>Robert Mackay</dc:creator>
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      <body xmlns="http://www.w3.org/1999/xhtml">
        <p align="justify">
          <font color="#000000">Although clinical trials with the aim to develop a safe and
efficient herpes vaccination can be dated back to 1920, there is no available cure
or immunisation for genital herpes at the current time. However, an early online publication
of a study in <i style="mso-bidi-font-style: normal">Nature</i> suggests that researchers’
are one step closer to developing a vaccination model which differs from previous
attempts.</font>
        </p>
        <p align="justify">
          <font color="#000000">Previous studies have primarily focused on the so-called T-cells,
which are known as the immune system’s anti bodies. Generally, when a virus or uncommon
bacteria is circulating in the body, the T-cells respond to it and also learn to recognise
it in case a future encounter will occur. Therefore, if a virus or some bacteria reappear,
then the T-cells are prepared to respond. However, this is not effective in all organs
as T-cells have restricted entry to the central nervous system, intestines, vagina
and lung airways.</font>
        </p>
        <p align="justify">
          <font color="#000000">In an attempt to circumvent this issue, the researchers’ have
utilised an alternative vaccination approach which entails “priming” and “pulling”.
The former consists of a conventional vaccination which aims to provoke a system-wide
T-cell response whereas the latter aims to recruit T-cells directly into the vaginal
tissue via an application of chemokine’s, which are known to help mobilize immune
cells. By using this methodology on female mice, the researchers’ key findings indicated
that it was possible for the T-cells to create a long-term niche and reduce the spread
of the virus into the sensory neurons.</font>
        </p>
        <p align="justify">
          <font color="#000000">Although this study was conducted by highly established researchers
at Yale Medical School, it is likely that a considerable amount of research is required
before these findings are translated to human treatment.</font>
        </p>
        <img width="0" height="0" src="http://www.thesticlinic.com/news/aggbug.ashx?id=79102573-35cd-40b2-9bc9-608fd7b5eb43" />
      </body>
      <title>Researchers Make Progress on Herpes Vaccine</title>
      <guid isPermaLink="false">http://www.thesticlinic.com/news/PermaLink,guid,79102573-35cd-40b2-9bc9-608fd7b5eb43.aspx</guid>
      <link>http://www.thesticlinic.com/news/2012/10/25/ResearchersMakeProgressOnHerpesVaccine.aspx</link>
      <pubDate>Thu, 25 Oct 2012 13:53:39 GMT</pubDate>
      <description>&lt;p align=justify&gt;
&lt;font color=#000000&gt;Although clinical trials with the aim to develop a safe and efficient
herpes vaccination can be dated back to 1920, there is no available cure or immunisation
for genital herpes at the current time. However, an early online publication of a
study in &lt;i style="mso-bidi-font-style: normal"&gt;Nature&lt;/i&gt; suggests that researchers’
are one step closer to developing a vaccination model which differs from previous
attempts.&lt;/font&gt;
&lt;/p&gt;
&lt;p align=justify&gt;
&lt;font color=#000000&gt;Previous studies have primarily focused on the so-called T-cells,
which are known as the immune system’s anti bodies. Generally, when a virus or uncommon
bacteria is circulating in the body, the T-cells respond to it and also learn to recognise
it in case a future encounter will occur. Therefore, if a virus or some bacteria reappear,
then the T-cells are prepared to respond. However, this is not effective in all organs
as T-cells have restricted entry to the central nervous system, intestines, vagina
and lung airways.&lt;/font&gt;
&lt;/p&gt;
&lt;p align=justify&gt;
&lt;font color=#000000&gt;In an attempt to circumvent this issue, the researchers’ have
utilised an alternative vaccination approach which entails “priming” and “pulling”.
The former consists of a conventional vaccination which aims to provoke a system-wide
T-cell response whereas the latter aims to recruit T-cells directly into the vaginal
tissue via an application of chemokine’s, which are known to help mobilize immune
cells. By using this methodology on female mice, the researchers’ key findings indicated
that it was possible for the T-cells to create a long-term niche and reduce the spread
of the virus into the sensory neurons.&lt;/font&gt;
&lt;/p&gt;
&lt;p align=justify&gt;
&lt;font color=#000000&gt;Although this study was conducted by highly established researchers
at Yale Medical School, it is likely that a considerable amount of research is required
before these findings are translated to human treatment.&lt;/font&gt;
&lt;/p&gt;
&lt;img width="0" height="0" src="http://www.thesticlinic.com/news/aggbug.ashx?id=79102573-35cd-40b2-9bc9-608fd7b5eb43" /&gt;</description>
      <comments>http://www.thesticlinic.com/news/CommentView,guid,79102573-35cd-40b2-9bc9-608fd7b5eb43.aspx</comments>
      <category>Herpes</category>
    </item>
    <item>
      <trackback:ping>http://www.thesticlinic.com/news/Trackback.aspx?guid=f1021abb-0286-46da-bfda-4b20ad5304ea</trackback:ping>
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      <dc:creator>Jamie Wilson</dc:creator>
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      <body xmlns="http://www.w3.org/1999/xhtml">
        <p align="justify">
          <font color="#000000">Recently a client of the e-Harmony dating website contracted
genital herpes, a lifelong virus that includes episodic breakouts and means that for
the duration of your life, you have the potential to be infectious and can pass the
virus onto other people through sexual activity. This woman took legal action against
the man who gave the virus to her since it had caused her harm both physically and
emotionally.</font>
        </p>
        <p align="justify">
          <font color="#000000">Over the last couple of years there have been a number of law
suits relating to the spread of herpes with intent. Many of these cases report that
the person being prosecuted did not know they were infectious, as was the case with
the e-Harmony client who passed the infection to his unsuspecting date.</font>
        </p>
        <p align="justify">
          <font color="#000000">With 1 in 6 people in the US reported to have herpes and with
condoms offering only some protection against this particular sexually transmitted
infection (STI), it can be difficult to avoid carriers if you have multiple sexual
partners. It is believed that around 10% of the UK population has the virus. The most
you can hope for is that a partner will tell you about their sexual history, however
embarrassing it might be for them but many of those infected do not know that they
remain infections even when they are not displaying obvious symptoms. Some think that
when they have had an outbreak and have treated it that the virus is gone for good.</font>
        </p>
        <p align="justify">
          <font color="#000000">Herpes will never go away and it is easily contracted. Looking
at the climbing STI rates all over the world, it is believable to think that some
individuals who pass it on are not aware that they are doing so and have not been
malicious in their intent but rather ignorant about the virus they carry. Questioning
a partner about their sexual history is vital before making the decision to engage
in sexual activity – although we understand that this can be awkward and can ruin
the moment.</font>
        </p>
        <p align="justify">
          <font color="#000000">Education is a huge factor and once again it seems the public
is largely ignorant as far as herpes is concerned. In the end the e-Harmony client
won damages and the jury stated that the woman taking action was 25% negligent versus
the man’s 75% negligence. There must be thousands who have contracted herpes in this
way and not many of them involve court cases.</font>
        </p>
        <img width="0" height="0" src="http://www.thesticlinic.com/news/aggbug.ashx?id=f1021abb-0286-46da-bfda-4b20ad5304ea" />
      </body>
      <title>Woman Successfully Sues for Herpes Transmission</title>
      <guid isPermaLink="false">http://www.thesticlinic.com/news/PermaLink,guid,f1021abb-0286-46da-bfda-4b20ad5304ea.aspx</guid>
      <link>http://www.thesticlinic.com/news/2012/06/15/WomanSuccessfullySuesForHerpesTransmission.aspx</link>
      <pubDate>Fri, 15 Jun 2012 17:13:46 GMT</pubDate>
      <description>&lt;p align="justify"&gt;
&lt;font color="#000000"&gt;Recently a client of the e-Harmony dating website contracted
genital herpes, a lifelong virus that includes episodic breakouts and means that for
the duration of your life, you have the potential to be infectious and can pass the
virus onto other people through sexual activity. This woman took legal action against
the man who gave the virus to her since it had caused her harm both physically and
emotionally.&lt;/font&gt;
&lt;/p&gt;
&lt;p align="justify"&gt;
&lt;font color="#000000"&gt;Over the last couple of years there have been a number of law
suits relating to the spread of herpes with intent. Many of these cases report that
the person being prosecuted did not know they were infectious, as was the case with
the e-Harmony client who passed the infection to his unsuspecting date.&lt;/font&gt;
&lt;/p&gt;
&lt;p align="justify"&gt;
&lt;font color="#000000"&gt;With 1 in 6 people in the US reported to have herpes and with
condoms offering only some protection against&amp;nbsp;this particular sexually transmitted
infection (STI), it can be difficult to avoid carriers if you have multiple sexual
partners. It is believed that around 10% of the UK population has the virus. The most
you can hope for is that a partner will tell you about their sexual history, however
embarrassing it might be for them but many of those infected do not know that they
remain infections even when they are not displaying obvious symptoms. Some think that
when they have had an outbreak and have treated it that the virus is gone for good.&lt;/font&gt;
&lt;/p&gt;
&lt;p align="justify"&gt;
&lt;font color="#000000"&gt;Herpes will never go away and it is easily contracted. Looking
at the climbing STI rates all over the world, it is believable to think that some
individuals who pass it on are not aware that they are doing so and have not been
malicious in their intent but rather ignorant about the virus they carry. Questioning
a partner about their sexual history is vital before making the decision to engage
in sexual activity – although we understand that this can be awkward and can ruin
the moment.&lt;/font&gt;
&lt;/p&gt;
&lt;p align="justify"&gt;
&lt;font color="#000000"&gt;Education is a huge factor and once again it seems the public
is largely ignorant as far as herpes is concerned. In the end the e-Harmony client
won damages and the jury stated that the woman taking action was 25% negligent versus
the man’s 75% negligence. There must be thousands who have contracted herpes in this
way and not many of them involve court cases.&lt;/font&gt;
&lt;/p&gt;
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      <category>Herpes</category>
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